Recent
First 'zap the crap', now 'Fry the fly': REIMS for insect identification
Iris Wagner, Natalie I. Koch, Joscelyn Sarsby, Nicola White, Tom A. R. Price, Sam Jones, Jane L. Hurst, Robert J. Beynon, (2020) The application of rapid evaporative ionisation mass spectrometry (REIMS) in the analysis of Drosophila species – a potential new tool in entomology [PDF] [PUBMED] [DOI] [Abstract...]
Using stable isotopes to track sperm competition
Paula Stockley, Catarina Franco, Amy J. Claydon, Amanda Davidson, Dean E. Hammond, Philip J. Brownridge, Jane L. Hurst, and Robert J. Beynon (2020) Revealing mechanisms of mating plug function under sexual selection. [PDF] [PUBMED] [DOI] [Abstract...]
Plasticity of the mouse seminal vesical fluid proteome
Helen L Bayram, Catarina Franco, Philip Brownridge, Amy J Claydon, Natalie Koch, Jane L Hurst, Robert J Beynon, Paula Stockley (2020) Social status and ejaculate composition in the house mouse [PDF] [PUBMED] [DOI] [Abstract...]
MS from gels, top down or bottom up
Ayako Takemori, David S Butcher, Victoria M Harman, Philip Brownridge, Keisuke Shima, Daisuke Higo, Jun Ishizaki, Hitoshi Hasegawa, Junpei Suzuki, Masakatsu Yamashita, Joseph A Loo, Rachel R Ogorzalek Loo, Robert J Beynon, Lissa C Anderson, Nobuaki Takemori (2020) PEPPI-MS: Polyacrylamide-Gel-Based Prefractionation for Analysis of Intact Proteoforms and Protein Complexes by Mass Spectrometry [PDF] [PUBMED] [DOI] [Abstract...]
An unusual marsupial urinary lipocalin - vulpeculin
Grace M. Loxley, David O. Hooks, Aristotelis Antonopoulos, Anne Dell, Stuart M. Haslam, Wayne L. Linklater, Jane L. Hurst and Robert J. Beynon (2020) Vulpeculin: a novel and abundant lipocalin in the urine of the common brushtail possum, Trichosurus vulpecula. Open Biology Open Biol. 10: 200218. http://dx.doi.org/10.1098/rsob.200218 [PDF] [PUBMED] [DOI] [Abstract...]
Using proteomics to explore 'pseudogene' expression
Ian Goodhead, Frances Blow, Philip Brownridge, Margaret Hughes, John Kenny, Ritesh Krishna, Lynn McLean, Pisut Pongchaikul, Rob Beynon and Alistair C. Darby (202o) Large-scale and significant expression from pseudogenes in Sodalis glossinidius – a facultative bacterial endosymbiont [PDF] [PUBMED] [DOI] [Abstract...]
Global proteomics of carbon source metabolism in Saccharomyces
M Garcia-Albornoz 1, S W Holman, T Antonisse, P Daran-Lapujade, B Teusink, R J Beynon, S J Hubbard (2020) A proteome-integrated, carbon source dependent genetic regulatory network in Saccharomyces cerevisiae. [PDF] [PUBMED] [DOI] [Abstract...]
Connective tissue protein turnover
Howard Choi, Deborah Simpson, Ding Wang, Mark Prescott, Andrew A Pitsillides, Jayesh Dudhia, Peter D Clegg, Peipei Ping, Chavaunne T Thorpe (2020) Heterogeneity of proteome dynamics between connective tissue phases of adult tendon. [PDF] [PUBMED] [DOI] [Abstract...]
Darcin and the neural circuits it activates
Ebru Demir, Kenneth Li, Natasha Bobrowski-Khoury, Joshua I Sanders, Robert J Beynon, Jane L Hurst, Adam Kepecs, Richard Axel (2020) The pheromone darcin drives a circuit for innate and reinforced behaviours [PDF] [PUBMED] [DOI] [Abstract...]
Using proteomics to identify targets for schistosomiasis
Leandro X Neves, R Alan Wilson, Philip Brownridge, Victoria M Harman, Stephen W Holman, Robert J Beynon, Claire E Eyers, Ricardo DeMarco, William Castro-Borges (2020) Quantitative Proteomics of Enriched Esophageal and Gut Tissues from the Human Blood Fluke Schistosoma mansoni Pinpoints Secreted Proteins for Vaccine Development. [PDF] [PUBMED] [DOI] [Abstract...]
REIMS for the analysis of bacterial protein production
Joscelyn Sarsby, Lynn McLean, Victoria M Harman, Robert J Beynon (2019) Monitoring recombinant protein expression in bacteria by rapid evaporative ionisation mass spectrometry. [PDF] [PUBMED] [DOI] [Abstract...]
Quantitative analysis of the yeast 'chaperome'
Rebecca J. Mackenzie, Craig Lawless [2], Stephen W. Holman, Karin Lanthaler, Robert J. Beynon, Chris M. Grant, Simon J. Hubbard and Claire E. Eyers (2106) Absolute protein quantification of the yeast chaperome under conditions of heat shock [PDF] [PUBMED] [Abstract...]
Structural comparison of central and peripheral mouse MUPs
Phelan MM, McLean L, Hurst JL, Beynon RJ, Lian LY. (2014) Comparative study of the molecular variation between 'central' and 'peripheral' MUPs and significance for behavioural signalling. [PUBMED][PDF]
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Quantification of proteins in the human osteoarthritic secretome
Peffers MJ, Beynon RJ, Clegg PD. (2013) Absolute quantification of selected proteins in the human osteoarthritic secretome. [PDF][PUBMED] [Abstract...]
QconCATs for mastitis research
Bislev SL, Kusebauch U, Codrea MC, Beynon RJ, Harman VM, Røntved CM, Aebersold R, Moritz RL, Bendixen E. (2012) Quantotypic properties of QconCAT peptides targeting bovine host response to Streptococcus uberis. [PUBMED][PDF] [Abstract...]
Extending Progenesis to embrace SILAC and Hi3
Qi, D., Brownridge, P., Xia, D., Mackay, K., Gonzalez-Galarza, F.F., Kenyani, J., Harman, V., Beynon, R.J. & Jones, A.R. (2012) A software toolkit and interface for performing stable isotope labelling and top3 quantification using Progenesis LC-MS OMICS [PUBMED] [PDF] [Abstract...]
Oxidative stress and MUPs
Garratt, M., McArdle, F., Stockely, P., Vasilaki, A., Beynon, R.J. Jackson, M.J. & Hurst, J.L. (2011) Tissue dependent changes in oxidative damage with male reproductive effort in house mice. [PDF] [Abstract...]